Biological Safety (or biosafety) has paralleled the development of the science of microbiology and its extension into new and related areas including tissue culture, recombinant DNA, animal studies, molecular biology, synthetic biology, and biotechnology. The Biosafety Program identifies practices, procedures, and operational standards for safe handling and use of biological materials, infectious agents and recombinant DNA molecules at Cal Poly State University. The National Institutes of Health (NIH), Center for Disease Control and Prevention (CDC), and Cal OSHA provide regulations and guidance in the operational standards contained in this program.